[acb-hsp] FW: Exciting News for Non-24 Sufferers!

[Peter Altschul]

  _____  

From: Annie Gallagher [mailto:Annie.Gallagher at vandapharma.com] 
Sent: Friday, February 24, 2012 10:00 AM
To: paltschul at centurytel.net
Subject: Exciting News for Non-24 Sufferers!

 

Dear Peter<first_name>,

 

The Vanda Outreach Team sincerely thanks you for your support of our
research on Non-24-Hour in individuals who are totally blind. We are excited
to share with you some exciting data of our ongoing clinical study and
invite you to share it with friends and family. 

 

Sincerely,

Annie Gallagher

The Vanda Outreach Team

Annie.gallagher at vandapharma.com

(240) 599- 4524

For more on Non-24 visit  <http://www.24sleepwake.com> www.24sleepwake.com,
follow us on Twitter  <http://twitter.com/#!/24SleepWake> @24SleepWake or "
<https://www.facebook.com/pages/24SleepWake/269350616423191?ref=nf&sk=wall>
Like" us on Facebook!

 

 

Subject: Exciting update and screening results for the Vanda Non-24-Hour
Studies in the Blind 

 

As many of you know, Vanda has been conducting research on a sleep problem
related to total blindness.  We have received many questions asking for
information about how the study is progressing and if it is working.  In a
press release on January 26, 2012, Vanda announced "tasimelteon was shown
for the first time to reset the body clock and to align it to a constant
24-hour day in patients suffering from Non-24-Hour Disorder (Non-24-Hour)."

 

In addition, we are pleased to be able to share some information from the
screening stage of the 3201 study that you may find interesting.  Examples
of the results include the fact that over 70% of those who are totally blind
with a sleep complaint were confirmed to have Non-24-Hour.  In addition, 50%
of patients experience an almost sleepless night (<2 hours of sleep) the
equivalent of once per month. This data shows how severe the sleep problems
can be in those who are affected and how common this condition is among
individuals who have no light perception.  

 

We want to thank everyone again for the support and participation that makes
this research possible and let you know Vanda has donated over $30,000 to
various organizations chosen by participants in the survey.  

 

Please share this information with any friends, family or colleagues who may
benefit from knowing about Non-24-Hour and encourage them to consider
participating.  We are close to completing enrollment but we need several
more people at each of our 23 research sites across the US to complete the
study.  Working together, we can help bring a treatment for Non-24-Hour to
those who need it.  More details on the data are below and the study
announcement with contact information is at the bottom of this message.

---------------

Vanda has submitted abstracts to the annual scientific sleep meeting planned
for June 2012 in Boston, MA.  Below are highlights of some of the
information that is planned for presentation at the sleep meeting.

 

Vanda has completed over 1,000 surveys of totally blind, no light perception
individuals.  Over 75% of participants taking the survey report one or more
of the following: trouble falling asleep, staying asleep, staying awake
and/or difficulty with napping.

 

For the 143 patients analyzed to date in the Non-24-Hour diagnosis stage of
the study, 70% received a confirmed diagnosis of Non-24-Hour.  The median
amount of time patients' body clock moved was over 3 hours per week, with
some people moving more than one hour every day. 

 

During the screening and diagnosis part of the trial, sleep diary
information highlighted some of the sleep problems caused by Non-24-Hour.
Over 50% of individuals with a Non-24-Hour diagnosis have the equivalent of
1 night per month with almost no sleep (<2 hours) and almost 10% have the
equivalent of 1 night per week with almost no sleep (<2 hours). 

 

In addition to the severe sleep problems, Non-24-Hour patients report
daytime napping that comes and goes depending on where their body clock is
relative to the normal day.  This napping is increased only when their body
clock is out of alignment with the normal day/night cycle and those with
Non-24-Hour do not show increased napping at times when their body clock is
aligned.

 

For more information on clinical studies and to take the survey, call
888-389-7033, visit www.non24registry.com or Email info at non24registry.com

 

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://www.acb.org/pipermail/acb-hsp/attachments/20120224/c99dfbae/attachment.html>