[acb-hsp] Marijuana, Alcohol and Nicotine: Gateway Drug

Mon Jul 16 12:30:19 EDT 2012

Well, Dr. Mercola and others would even disagree about alcohol. What about the pharmaceutical industry and doctors who are prescribing voocoos of Ritalin, Cylert, Aderil, and

...read on

to our kids?

thatStory at-a-glance

Purdue Pharma, the makers of the highly addictive painkiller OxyContin, is now doing

clinical tests to get the drug approved for kids as young as 6-years old. Such pain

killers have now been shown to be the primary gateway drug of choice, beating out

marijuana, smoking and alcohol, and the consequences are far deadlier.

On July 2, the British drug maker GlaxoSmithKline plead guilty to three counts of

criminal misdemeanor and other civil liabilities relating to the prescription drugs

Paxil, Wellbutrin and Avandia, and agreed to pay a total of $3 billion in fines.

The payment is the largest fraud settlement in U.S. history, and the largest fine

ever paid by a drug company.

TV and radio personality Dr. Drew Pinsky (aka "Dr. Drew," of sex-advice-giving fame)

allegedly accepted $275,000 to illegally promote GSK's antidepressant Wellbutrin

for sexual dysfunction

According to a 2010 report by the Public Citizen's Health Research Group, just four

companies, including GlaxoSmithKline, accounted for more than half of all financial

penalties imposed against pharmaceutical companies over the past two decades

It has become abundantly clear that fines do NOT work. To dampen the rampant criminal

behavior enveloping the drug industry, individuals responsible for and complicit

with these criminal acts must face criminal charges

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GlaxoSmithKline: GUILTY in Largest Health Fraud Settlement in US History

July 16 2012

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Glaxo to Pay $3 Billion to Settle U.S. Charges - YouTube

The British pharmaceutical company GlaxoSmithKline has plead guilty and will pay

$3 billion to resolve criminal and civil liability charges related to illegal drug

marketing and withholding information about health hazards associated with its diabetes

drug Avandia.

Visit the Mercola Video Library

By Dr. Mercola

One of the biggest news stories relating to health right now is the finalization

of the biggest lawsuit yet by the American government against a pharmaceutical company.

On July 2, the British drug maker GlaxoSmithKline plead guilty to three counts of

criminal misdemeanor and other civil liabilities relating to the prescription drugs

Paxil, Wellbutrin and Avandia, and agreed to pay a total of $3 billion in fines--$1

billion to settle criminal charges, and $2 billion to cover civil liabilities.

The payment is the largest fraud settlement in U.S. history, and the largest fine

ever paid by a drug company.

In 2009, Pfizer paid $2.3 billion to settle similar charges

1

, and as recently as May, Abbott Laboratories settled charges over wrongful marketing

of the anti-seizure drug Depakote to the tune of $1.6 billion

2

. The company had illegally promoted the drug to health care providers for off-label

use in seniors with dementia.

And, according to a July 6 report in the Huffington Post

3

, a federal investigation into wrongful marketing by Johnson & Johnson of its antipsychotic

drug Risperdal is also wrapping up and may result in a fine of anywhere between $1.6

to 2 billion.

According to FiercePharma's recent compilation of the Top 11 marketing settlements

by the drug industry over the past 10 years

4

, drug makers have agreed to pay more than $11 billion in fines for their illegal

marketing shenanigans over the past decade! But the worst may still lie ahead: more

than 900 whistleblower lawsuits were filed in the last year alone and historically

about 10 percent of whistleblower claims involve drugmakers...

While these fines sound like staggering amounts of money to most people, a fundamental

problem has now become blatantly and painfully apparent, and that is that

fines don't work

. They simply do not curtail criminal behavior when applied to faceless corporations.

They've become little more than an expected annoyance that are calculated into the

price of doing business.

Meanwhile, average people are paying for the criminal behavior of these "corporate

personhoods" with their very lives.

Keep in mind that while "wrongful marketing" may not sound like a big deal, we're

not talking about a toy that you can't play with in the manner advertised. We're

talking about extremely potent chemicals that alter brain and biological chemistry.

When you consider how shoddy and fraught with conflicts of interest the approval

process is to begin with-as poorly tested drugs are approved with increasing frequency

and must later be withdrawn-it should be frighteningly obvious how dangerous it can

be to market drugs for

unapproved

uses.

GlaxoSmithKline Guilty of Illegal Marketing and Withholding Hazard Info

When GSK began targeting children, Paxil became a top 10 selling drug with annual

sales in excess of $1.8 billion in 2001 and 2002 alone. This is particularly grievous

as, according to the Justice Department's complaint

5

, several clinical studies on Paxil involving children and adolescents, performed

in the mid- to late-90's, had ALL FAILED to demonstrate efficacy on this age group!

Every single one of them!

According to the US Justice Department

6

, GlaxoSmithKline:

1. Unlawfully marketed the antidepressant Paxil to children and adolescents.

The drug is FDA approved for the treatment of depression in adults only.The complaint

details how GSK manipulated the findings of one of these studies to reach the false

conclusion that Paxil was effective against depression in adolescents. A GSK employee

also recommended revising a section of the study relating to side effects, removing

the finding that serious side effects like worsening depression and hostility (suffered

by 11 children in the study) were considered related to the treatment, and replacing

it with a statement that headache (suffered by one participant) was the only side

effect considered to be treatment-related.

The complaint calls the study, published in July 2001 in The Journal of American

Academy of Child and Adolescent Psychiatry

, "

false and misleading

." This fraudulent and misleading study was subsequently used by GSK to illegally

promote Paxil for children and teens...

2. Unlawfully marketed the antidepressant Wellbutrin for weight loss and sexual

dysfunction.

In a recent NPR radio interview

7

, Carmen Ortiz, U.S. Attorney for the District of Massachusetts, stated that "GSK

hired a public relations firm to create a buzz about getting skinny and how you could

have more sex simply by using this drug...using every imaginable form of high-priced

entertainment, from Hawaiian vacations to paying doctors millions of dollars to go

on speaking tours, to a European pheasant hunt, to tickets for Madonna concerts."

3. From 2001 through September 2007, failed to report safety data relating to clinical

experience and other information as required by law to the FDA for the diabetes drug

Avandia

.

As previously reported,

Avandia

has been found to be profoundly dangerous-a fact hid by GSK for over 10 years, as

they knew it would adversely affect sales

8

. This was revealed in a Senate Finance Committee report, released by Max Baucus

and Charles E. Grassley in February 2010. The report also asked why the FDA allowed

a clinical trial of Avandia to continue even after the agency estimated the drug

had caused an estimated 83,000 heart attacks between 1999 and 2007

9

.

Avandia hit the market in 1999 and quickly became a blockbuster drug. By 2006 its

annual revenue was $3.2 billion. A year later, a damning study published in the

New England Journal of Medicine (NEJM) linked it to a

43 percent increased risk of heart attack

and a 64 percent higher risk of cardiovascular death than patients treated with

other methods

10

.

This is a steep price, to say the least, for a disease that does not require drugs

to begin with, and Avandia has become a poster child for the lethal paradigm of faux

science.

Why Isn't Someone Going to Jail??

According to the July 2 press release issued by GSK

11

, the criminal and civil liabilities resolved by this final agreement also include

inappropriate marketing of six other drugs, and "possible inappropriate use of the

nominal price exception under the Medicaid Rebate Program."

One aspect that truly

worries me is that while the criminal cases we've seen in the past several years

are related to drugs, many of these companies, including GSK, also produce VACCINES.

And guess what?

They're typically not liable

for damages from, or harm done by, contaminated or otherwise dangerous vaccines!

We've recently seen evidence of

"mistakes" in vaccine manufacturing

as well, but vaccine makers are rarely if ever punished for these willful errors

and omissions, which should provide you some further food for thought.

Celebrity Doctors Paid to Illegally Promote Dangerous Drugs

A few days after the US Justice Department reached its agreement with GSK, it was

revealed that TV and radio personality Dr. Drew Pinsky (aka "Dr. Drew," of sex-advice-giving

fame) allegedly accepted $275,000 to carry out the illegal promotion of GSK's antidepressant

Wellbutrin. Dr. Pinsky is said to have highlighted the drug's libido-enhancing side

effects on a number of occasions in 1999

12

,

13

.

While Dr. Drew is the one in the news right now, he's not the only TV and radio doctor

who's accepted money from drug companies to push their products to an unsuspecting

public. For example, Dr. Marie Savard

14

, who has appeared on dozens of TV shows such as

Good Morning America, ABC News, and Oprah, is paid by Merck to pitch their HPV vaccine.

According to a July 3 report in the Wall Street Journal

15

:

"In June 1999, popular radio personality Dr. Drew Pinsky used the airwaves to extol

the virtues of GlaxoSmithKline's antidepressant Wellbutrin, telling listeners he

prescribes it and other medications to depressed patients because it "may enhance

or at least not suppress sexual arousal" as much as other antidepressants do.

But one thing listeners didn't know was that, two months before the program aired,

Dr. Pinsky-who gained fame as "Dr. Drew" during years co-hosting a popular radio

sex-advice show "Loveline"-received the second of two payments from Glaxo totaling

$275,000 for "services for Wellbutrin."

...

Doctors are allowed to prescribe drugs as they see fit, but it is illegal for companies

to promote drugs for uses not approved by the FDA, a practice known as "off-label"

marketing. Wellbutrin's prescribing label doesn't state that the drug is less inhibiting

of sexual libido than other antidepressants. In an email Tuesday, Glaxo declined

to answer questions about its financial relationship with Dr. Pinsky or other physicians.

The company said: "The complaint to which you refer concerns events in 1999, 13 years

ago. It does not reflect what would be allowed in GSK today."

I for one do not buy into any of this drivel about how things have changed... If

anything, the evidence tells us that illegal and unethical behavior of corporations

like GSK has WORSENED and solidified into standard

modus operandi

over the past decade. Case in point: According to a 2010 report by the Public Citizen's

Health Research Group, titled "

Rapidly Increasing Criminal and Civil Monetary Penalties Against the Pharmaceutical

Industry: 1991 to 2010

"

16

:

"Of the 165 settlements comprising $19.8 billion in penalties during this 20-year

interval,

73 percent of the settlements (121) and 75 percent of the penalties ($14.8 billion)

have occurred in just the past five years (2006-2010).

Four companies (GlaxoSmithKline, Pfizer, Eli Lilly, and Schering-Plough) accounted

for more than half (53 percent or $10.5 billion) of all financial penalties imposed

over the past two decades.

These leading violators were among the world's largest pharmaceutical companies."

As I've reported before, pharmaceutical companies accounted for nearly 20 percent

of the top 100

Corporate Criminals

in the 1990's, and there's NO evidence to indicate that these shenanigans are in

fact on the decline...

Bill Gates Connection to Glaxo Drug Fraud Scandal

Even the Gates Foundation has been linked to this massive scandal through the swinging

doors of employment. According to a July 3 report by Tom Paulson on KPLU 88.5

17

:

"Most news reports quoted GSK's CEO Andrew Witty blaming the misconduct on others

and "a different era for the company," adding that such behavior will not be tolerated...

One of the most high-profile GSK executives alleged to have engaged in misbehavior

is Tachi Yamada, former head of global health for the Bill & Melinda Gates Foundation

who was before that head of research and development for GSK.

Yamada, while he was head of global health for Gates Fdn, was accused in a U.S. Senate

hearing of bullying a scientist to not publish negative findings about a GSK diabetes

drug. This was fairly big news at the time and such behavior is part of the federal

complaint against the drug firm... But so far as I can tell, nobody has made any

mention of Yamada's role in this case. Yet he was pretty high profile - at the center

of the controversy surrounding the drug company's attempt to cover-up adverse side

effects of its diabetes drug Avandia.

... Yamada... recently left the Gates Foundation to work for a Japanese drug company...

But there's no getting away that Yamada played a leading role in the largest health

fraud case in American history and that, given his much greater influence as head

of a philanthropic program that many say sets the agenda for global health, it might

be worth mentioning."

Indeed, the Gates Foundation is deeply entrenched in an unholy alliance with both

Big Pharma and Monsanto. For example, 2011 Wikileaks documents detailed the alliance

between the U.S. State Department and the

Gates Foundation Alliance for a Green Revolution in Africa

(AGRA) to promote the private interests of Monsanto in an effort to turn Africa

into a GMO-friendly continent. H

igh level officials leading AGRA are in fact former Monsanto executives, and the

Gates Foundation also owns Monsanto stock.

Other ties that bind the Gates Foundation to Big Pharma and Monsanto include the

following close associations:

Vice president of Monsanto Robert Horsch joined the Gates Foundation in 2006

Merck CEO Raymond Gilmartin was placed on the Gates Foundation Board of Directors

in 2001

Gates invested $205 million in nine of the large pharmaceutical companies in 2002

Why are Children Sacrificed as Guinea Pigs?

GSK and the rest of the Big Pharma cronies want you to believe that "things have

changed;" that they've "learned from their mistakes," and that everything is fine

now since the real wrongdoers like Tachi Yamada have moved on to other venues.

Now

, they promise, your health and well-being is at the forefront of everyone's mind

working in the pharmaceutical industry. Think again. A recent story on TechDirt.com

18

really underscores the perverse nature of drug company greed:

"... Purdue Pharma, the makers of the highly addictive painkiller OxyContin, is now

running clinical tests to get the FDA to approve its use for kids as young as 6-years

old

19

.

Why?

Because the Federal Food, Drug, and Cosmetic Act section 505A

20

includes a little "gift": if drugmakers conduct clinical studies for their drugs

with kids, they can get six more months of patent protection. So even if they don't

even sell OxyContin to six year olds, just securing the extended patent, thanks to

the massive monopoly rents given to drugs still on patent, Purdue is likely to profit

massively. Lots of people are reasonably troubled by this:

"They are doing (the pediatric trial) for patent exclusivity, there's no doubt about

it in my mind - not out of largesse," said Dr. Elliot Krane, director of pain management

at Lucile Packard Children's Hospital at Stanford University in Palo Alto, Calif..."

This is about as crazy as it gets, folks. How many young children could possibly

be in need of a potent narcotic pain reliever like OxyContin? Not to mention the

fact that this particular drug has been identified as one of the absolute most problematic

in terms of drug abuse and death. To say that the incentive for this kind of drug

trial is questionable would be an understatement. It's downright abhorrent, and it

speaks volumes about the ethics, or rather lack thereof, that drives the pharmaceutical

industry as a whole.

Prescription Painkillers: New "Gateway Drug"

For the longest time marijuana, smoking and alcohol were the first drugs of choice

by those who later may move into more hard-core drugs; hence the term "gateway drug."

But things have changed a lot in recent years. Prescription drugs-especially prescription

pain killers like OxyContin-are now leading the pack as the most common "gateway"

to illegal drug use, and the consequences are far deadlier.

According to a July 6 press release

21

:

"... Since 2000, the drugs sending people to their graves or to rehab have been shifting

away from illicit drugs and toward prescription drugs. The 2011 report on the subject

from the Centers for Disease Control and Prevention made it clear:

prescription narcotic pain reliever overdose deaths now exceed the number of deaths

from heroin and cocaine combined

.

For decades now, it has been usual that many young people looking for a drug to experiment

with for the first time would choose marijuana... The Narconon Arrowhead drug rehabilitation

program has recently uncovered a new pattern since

prescription opiates have increasingly become the first drug used by many young

people

. This pattern is backed up by government surveyed results. According to Michael

Botticelli, Director of the Massachusetts Bureau of Substance Abuse,

prescription drugs now equal marijuana as entry-level drugs.

... "Our own clients and people calling in daily for information about our program

or help have told us story after story about addictions starting with the use of

prescription drugs," stated Derry Hallmark, Director of Admissions at Narconon Arrowhead,

a premier drug rehab facility in Southeastern Oklahoma. "Sadly, prescription medications

have become the newest of the gateway drugs. Sadder still are the losses of life

and other severe consequences that go hand in hand with drug abuse, which is especially

the case with prescription drug abuse."

Hallmark adds that those addicted to prescriptions will often end up needing treatment

or will even start taking illicit drugs.

One of the most common examples of this is the connection between those addicted

to painkillers that then start taking heroin

..."

Fines Alone Cannot Change Drug Co. Criminality

It has become abundantly clear that fines do NOT work. In order to see any changes

whatsoever in the rampant criminal behavior enveloping the drug industry, the Justice

Department must slap criminal charges on the individuals responsible for, and complicit

with, these criminal acts. Quite simply, those engaging in fraud need to know they

can be held personally liable and face time in federal prison for their crimes.

A number of recent articles in the press have highlighted this now obvious fact,

and brought up related issues that really need to be addressed. For example, Judith

Warner, writing for

Time Magazine states:

"... we are confronted, yet again, with the fact that these fines, however punitive-seeming

on their face, are chump change in comparison to the company's bottom line and highly

unlikely to bring real change to its - or, indeed, the industry's - future practices...

Glaxo wasn't exactly ruined by the fines:

In the years covered by the settlement, the company had earned $10.4 billion in sales

of Avandia, $11.6 billion from Paxil, and $5.9 billion from Wellbutrin

...

A number of commentators... argued that seeking monetary damages isn't going to change

most problematic practices of the pharmaceutical industry. Instead, they say, we

should seek criminal charges against specific executives, the risk of jail time being

the only way to actually change behavior. Though such a solution certainly offers

the prospect of some real gut-level satisfaction, I'm not convinced that it will

actually show results. (Given the enormous resources, legal and otherwise, of the

drug companies, I think it's fair to assume that they'd be quickly able to figure

out methods of Teflon-shielding their executives.)

Such a strategy also

doesn't address the fundamental problems that have enabled, if not created, Big Pharma's

repeat bad behavior: a balance of power between the industry and our government that

is seriously askew, and a particular lack of smart regulation

... over the way information about specific drugs is controlled, verified, and disseminated."

[Emphasis mine]

She brings up an excellent point, which is that the entire system is broken and a

number of changes need to be implemented to put an end to this no-holds-barred profit-driven

era of faux-science-derived medicine. The health care system is driven and controlled

by Big Pharma, which churns out a mind-boggling amount of faked and flawed science

to justify its recommendations, while simultaneously purchasing the "right" to monopolize

the health industry via strategically placed industry lackeys in various positions

of political and federal power.

Still, I believe holding individuals

accountable for the criminal activities performed under the auspice of corporate

personhood is a must, and would serve as a good starting point to weed out the most

heinous psychopaths.

Robert Reich,

Chancellor's Professor of Public Policy at the University of California and former

Secretary of Labor in the Clinton administration also addressed this issue in a recent

Huffington Post article, and brought up two more vital points of contention that

need to be addressed

22

:

"... Not a single executive has been charged -- even though some charges against

the company are criminal. Glaxo's current CEO came on board after all this happened.

Glaxo has agreed to reclaim the bonuses of any executives who engaged in or supervised

illegal behavior, but the company hasn't officially admitted to any wrongdoing -

and without legal charges against any of executive it's impossible to know whether

Glaxo will follow through... The only way to get big companies like these to change

their behavior is to make the individuals responsible feel the heat.

An even more basic issue is

why the advertising and marketing of prescription drugs is allowed at all, when consumers

can't buy them and shouldn't be influencing doctor's decisions anyway

. Before 1997, the Food and Drug Administration banned such advertising on TV and

radio.

That ban should be resurrected.

Finally,

there's no good reason why doctors should be allowed to accept any perks at all from

companies whose drugs they write prescriptions for

. It's an inherent conflict of interest. Codes of ethics that are supposed to limit

such gifts obviously don't work.

All perks should be banned, and doctors that accept them should be subject to potential

loss of their license to practice

." [Emphasis mine]

Final Thoughts

Mark my words, this will not be the last time we'll learn more than we've ever wanted

to know about the seedy underbelly of the pharmaceutical industry. The real take-home

message from all this is that the ultimate responsibility for your health lies with

you. Always remember that drugs are rarely anything more than a short-term band-aid

to your health problems.

Some drugs are convenient short-term fixes for acute problems (like a headache),

for which most of us are grateful, but problems arise when you believe the deception

these multi-national drug corporations have created, and choose drugs as the long-term

answer to your health challenges. It doesn't really matter whether the drug has been

approved for your particular ailment or is being recommended off-label-the risks

are much the same.

Life would be grand if we could just swallow a pill and all our health problems would

be solved. But believing this fairy tale will only make these companies wealthier,

while putting you at risk for serious side effects or even death, like the 80,000+

men and women who chose Avandia as their band-aid solution and ended up with a drug-induced

heart attack...

My advice: Strive to better understand and treat the real problem behind your medical

condition. There are hundreds of thousands of pages of free information on this site

designed to help you achieve that goal and help you and your family Take Control

of Your Health. Remember to use the site search engine located at the top of every

page to find more information on your health questions.

References:

See All References

Sources:

Star-Tribune July 5, 2012

BBC Audio Link July 6, 2012

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